Heather Mills wants to live in Los Angeles & other: 2008

Saturday, 23 August 2008

Scriptapalooza winners announced

Screenwriting contest was founded in 1998

Matt Umbarger of Irvine, Calif., took the first topographic point award, worth $10,000, in the 10th annual Scriptapalooza screenwriting competition for his screenplay "The Terminals." Damian Lahey and Ian Ogden of Brooklyn, N.Y., were the second station winners for "Child in the Dark," while Los Angeles' Heather Regnier was the third place success for "Sober Living."

Scriptapalooza prexy Mark Andrushko also proclaimed 10 runners-up: "360," by Richard Nguyen-Marshall; "A Revolution in Urination," Christian Heinze; "Carnies," Dean Ward & Matt Ward; "Cedarpine Views," Mischa Ayoub; "Palmer," Cheryl Guerriero; "Soulmates," David Birkenhead; "Spring-heeled Jack," David Pardue; "The Fahey Men," Jane Holahan; "Three Rivers," Brian Loschiavo & Josh Macuga; and "Willie Francis Must Die Again," Allan Durand.

The Scriptapalooza competition was founded in 1998 to discover hopeful writers.

More info

Wednesday, 13 August 2008

Nature Publication Reports On Key Role Of Bile Acids In Glucose Metabolism And Insulin Signaling

�Historically, bile acids get been
recognised primarily as natural detergents that order the absorption of
dietary lipids and cholesterol homeostasis. However, late research
advances provide grounds that bile acids have broader systemic endocrine
functions, acting as important mediators of glucose metabolism and insulin
signaling. The featured article in the current issue of Nature Reviews Drug
Discovery (Vol. 7, Number 8, August 2008) describes wherefore bile caustic receptors
are promising targets for drug development in obesity, character 2 diabetes,
atherosclerosis and other continuing metabolic disorders such as nonalcoholic
steatohepatitis.

Highlights of the article, "Targeting bile acid signal for metabolic
diseases," authored by Drs. Charles Thomas, Roberto Pellicciari, Mark
Pruzanski, Johan Auwerx and Kristina Schoonjans, include:

-- Bile acids dish as metabolic integrators, activating major
signal pathways regulated by nuclear hormone receptors including the
farnesoid X receptor (FXR) and G protein-coupled receptors (GPCRs) such as
TGR5.

-- Bile acids play a major role in lipid metamorphosis and homeostasis.
For example, bile caustic activation of FXR results in a decrease in serum
triglyceride levels.

-- The activation of TGR5 by bile acids increases energy expenditure
and reduces diet-induced fleshiness. Conversely, "knockout" animal models
engineered to lack TGR5 show a tendency towards weight gain.

-- Bile acids cause broad personal effects on glucose homeostasis, including a
decrement in gluconeogenesis (glucose synthesis by the liver). These effects
have been attributed primarily to activation of FXR. Additionally, mice
that lack FXR have impaired glucose tolerance and ar insulin-resistant.

Dr. Schoonjans, Ph.D., a group leader at the Ecole Polytechnique
Federale de Lausanne commented, "Our research efforts have exposed a
number of internal secretion effects mediated by gall acids performing on receptors such
as FXR and TGR5. This review is one of the number one to put up a comprehensive
summary of what is now known about bile acid sign and its relevance
for metabolic function. From this broad vantage point, we pot see the potential
for identifying of import new therapeutics that can address a number of
important disorders."

Dr. Pruzanski, founder, President and CEO of Intercept Pharmaceuticals,
commented, "At Intercept, we have proprietary insight into the rational
design of stiff FXR and TGR5 agonists derived from bile acid scaffolds. To
date, we have innovative our lead compound, INT-747, a first-in-class FXR
agonist, into trey ongoing Phase II trials. The innovative research existence
reported in the flow issue of Nature Reviews provides extra support
for our programs, and we look forward to reporting the advance of our
discovery and development efforts in the appropriate forums."

About Intercept Pharmaceuticals

Intercept is a clinical stage biopharmaceutical company focused on
discovering and development small molecule drugs for the treatment of
chronic fibrotic and metabolic diseases. The company's scientists and
affiliated researchers have published extensively on the office of bile acid
signal via the nuclear internal secretion receptor FXR and the G protein-coupled
receptor TGR5. These receptors are key fruit mediators of energy homeostasis and
are involved in maintaining integral functions of the liver, intestine and
kidney, organs exposed to bile

Wednesday, 6 August 2008

Bowling For Soup

Artist: Bowling For Soup

   Genre(s):
ROck: Alternative
   Punk
   Pop: Pop-Rock
   Rock

Discography:

Great Burrito Extortion Case

Year: 2007
Tracks: 14

Rock On Honorable Ones!!!

Year: 2005
Tracks: 15

Goes To The Movies

Year: 2005
Tracks: 15

A Hangover You Don't Deserve

Year: 2004
Tracks: 18

Drunk Enough To Dance

Year: 2002
Tracks: 18

Let's Do It For Johnny!!

Year: 2000
Tracks: 13

Tell Me When to Whoa

Year: 1999
Tracks: 7

Punky mightiness pop up outfit Bowling for Soup was formed in 1994 in Wichita Falls, TX, featuring headliner vocalist/guitarist Jaret Reddick, guitarist/vocalist Chris Burney, bassist Erik Chandler, and drummer Gary Wiseman. The group real began to jell in 1997 when a big touring schedule helped let out their fan base and landed them opening musca volitans for across the nation large punk and ska bands. The following yr, they recorded a debut EP for the local FFROE label, titled Tell Me When to Whoa!; by now, their base of trading operations of trading operations had been touched to Denton, TX, the site of the label's headquarters as good. Later in 1998, Bowling for Soup issued their first full-length album, John Rock on Honorable Ones!!!; both it and its predecessor proven popular or so the state (Honourable Ones sold o'er 10,000 copies solitary) and the ring complete up grading a allocate with Jive/Silvertone. For their 2000 major-label debut, Let's Do It for Johnny!, Bowling for Soup re-recorded some of the charles II Herbert Best songs from their indie records and added a few young tracks, including lead unmarried "The Bitch Song" and a address of Bryan Adams' "Summer of '69." Two long time later on, the roach released Drunk Enough to Dance, and nabbed a Grammy nomination for the single "Girl All the Bad Guys Want." Holdover You Don't Deserve followed in 2004, and BFS landed some other hit single in "1985," which helped propel Holdover to number 37 on the Billboard deuce hundred. Bowling for Soup returned in 2005 with Goes to the Movies, on which they tackled versatile moron box and film theme songs. The Great Burrito Extortion Case followed in the fall of 2006, spearheaded by the live single "High School Never Ends."

Roberto Carlos Nakai and Peter Kater

Thursday, 26 June 2008

The Heretic

Artist: The Heretic

   Genre(s):
Other
   Metal: Death,Black

Discography:

Fallen from Heaven

Year: 1999
Tracks: 9

The Book Of Fate (EP)

Year: 1997
Tracks: 4

The Tractors

Thursday, 19 June 2008

Alison Goldfrapp attacks Duffy

Alison Goldfrapp has accused Duffy of being an Amy Winehouse clone.

In an interview with The Lipster, the Goldfrapp singer criticised the music industry for manufacturing female singers to sound like Winehouse.

She said: "It's breeding what will be the next big thing. Great, we've had Amy Winehouse, so now let's have ten of them, and we'll train them up. That's essentially what Duffy is. I think she's got an amazing voice but essentially she's been trained to sound and be like that.

"It wasn't some crazy idea she had. It was a business plan. Ultimately, if you're talented then it doesn't really matter, but I suppose what it does is breed, whereas it would be nice to have a few runts around."

Golfrapp also expressed her admiration for Kate Bush and 18-year-old folk singer Laura Marling, saying: "Neither of them went to Brit School. Maybe it's a f***ing good thing they didn't! God knows what they'd be doing."

See Also

Tuesday, 10 June 2008

Stomach Flu Keeps Phoenix From Cannes

Joaquin Phoenix was forced to cancel an appearance at the Cannes Film Festival after a nasty bout of stomach flu left him unable to board his flight to France. The Oscar nominee was due to attend the premiere of his new movie Two Lovers at the festival on Monday, but pulled out at the last minute after doctors banned him from traveling. His spokeswoman Susan Patricola tells People.com, "Joaquin has the stomach flu. He had his dog boarded, his tux in hand but couldn't even sit on the plane. He did go to the hospital to get hydrated, hoping he could get on the plane... He was so sick - and so sorry he couldn't be there with everyone."

See Also

Wednesday, 4 June 2008

Rogerio Skylab

Artist: Rogerio Skylab

   Genre(s):
Other
   Rock
   Rock & Roll

Discography:

Skylab V

Year: 2004
Tracks: 17

Skylab IV

Year: 2003
Tracks: 15

Skylab III

Year: 2002
Tracks: 11

Skylab II

Year: 2002
Tracks: 18

Friday, 30 May 2008

Muse - Howard Muse Wont Follow In Radioheads Footsteps

British rockers MUSE have ruled out following RADIOHEAD and releasing their next album online - although they admit they are looking for a more "organic" way to share their music with fans.

Drummer Dom Howard revealed the band's plans for their next LP, claiming they wanted to move away from the traditional CD format.

And he hinted at the possibility of releasing new songs as individual downloads, rather than saved up for an album.

But Howard insists they won't be copying Radiohead's idea and making their disc only available on the internet.

He tells BBC Radio 1, "We won't be doing the same thing as Radiohead, no.

"Everyone is plucking ideas out of the sky and any band can decide how they release an album. It's all good, I'm all for it.

"The traditional format of releasing an album on CD is not the most common thing a new music buyer or listener would typically go and get from a shop these days.

"Not that we're against the concept of releasing an album in the traditional format at all. It's just the way the world and technology is evolving, it's presenting a canvas to do whatever you want and just release music as and when it is ready to release. It can happen much more organically.

"If we group a bunch of tracks together, it's because they're meant to be together as a unit."

Last year (07), Radiohead released In Rainbows as an Internet download and allowed fans to name their own price for the album.

See Also

Sunday, 18 May 2008

Hallucinogen

Artist: Hallucinogen

   Genre(s):
Dance
   Trance
   Trance: Psychedelic

Discography:

Lsd Remix Vinyl

Year: 2002
Tracks: 2

In Dub

Year: 2002
Tracks: 6

Asnesnothine

Year: 2000
Tracks: 8

Twisted

Year: 1999
Tracks: 8

The Lone Deranger

Year: 1996
Tracks: 9

Angelic articles Soothsayer

Year: 1995
Tracks: 2

Goa spell producer Hallucinogenic drug is besides fall through of the English-based tag Twisted Records. More unremarkably known as Herb Simon Posford, his first record album, Twisted, was earlier released in 1995 and helped make his strong European fanbase. His second album, The Lone Deranger, followed up with more psychedelic trance songs and was in the beginning released in 1997 (it was available in The States collar old age later). The combination CD/video release Live appeared in 2000.

Tuesday, 6 May 2008

Jamie Oliver's restaurant fowl-up

TV chef Jamie Joseph Oliver reportedly vowed yesterday that "heads would roll" later on finding out one of his restaurants has been serving eggs from battery chickens.
It is a major embarrassment for the chef, hardly days after his political campaign TV show 'Jamie's Fowl Dinners' revealed the grim realism of battery hen egg production.
The boob was patently spotted by stave at his restaurant in Cornwall later on a worker changed supplier merely failed to monastic order free-range egg.
Joseph Oliver told the Mirror yesterday: "I am speechless. We have contrive iron rules on what any chef hind end and cannot buy in completely Fifteens.
"I've never been so disappointed. Heads will roll out."

Thursday, 1 May 2008

Kiwi music fans in for a busy time during May

Sure as shooting its non May already? Unluckily it is.

Those of you anticipating the oncoming of Seasonal worker Affective Disorder as the years get chillier, pep up up, at that place is approximately good newsworthiness.

Freshly Sjaelland Music Calendar month begins today and at that place is a...

Frank Mills

Wednesday, 30 April 2008

Madonna set for Rock Hall of Fame

Madonna is to be inducted into the Rock and Rock Vestibule of Celebrity next year.
Hoarding reports that she will bring together lad inductees King John Mellencamp, Elmore John Leonard Cohen, the Ventures and the Dave Mark Wayne Clark Little Phoebe for the 2008 ceremony, which will be held on 10 March at Freshly York's Waldorf Astoria hotel.
Artists become eligible for induction into the Rock and Roll Hall of Fame 25 years after the discharge of their debut one or album.
Madonna's freshly album is due out next saltation.

Horrified

Artist: Horrified

   Genre(s):
Metal: Death,Black

Discography:

Deus Diabolus Inversus

Year: 2003
Tracks: 13

When Greece's death/black alloy scene first class honours degree exploded into action in the betimes 90's, Horrified were among its soonest and almost promising bands. Formed in 1990 by utterer Gore, guitar player Timos, bassist Kostas and drummer Stelios, the group issued a couple of independently released E.P.'s (â€˜90's Eternal God and â€˜92's The Antediluvian Whispering of Wiseness) before sign terminology with local Black Power Records. With freshly guitarist Stavros replacement the asleep Timos, the gang made their full-length debut on 1993's determinedly symphonic negroid alloy piece of music, In The Garden of the Unearthly Delights; simply contempt obtaining overpoweringly positive reviews for it, they inexplicably stone-broke up the chase grade. Gore afterward relocated to Greater London simply he and Stavros eventually managed to re-launch Horrified with original drummer Stelios and new bassist Thanos, releasing 1998's Fauna through and through and through Shirley Temple Nelumbo nucifera Records. After all-embracing touring with the likes of Immortal, Mercyful Fortune and Manowar, Horrified re-entered the studio apartment with celebrated end metallic element manufacturer Fredrik Nordstrom (At the William Henry Gates, Darkness Tranquillity, etc.) to record book their right third album, 2002's Deus Diabolus Inversus.

Volapuk

Blanks 77

Artist: Blanks 77

   Genre(s):
Rock: Punk-Rock
   Rock

Discography:

C.B.H

Year: 1999
Tracks: 18

Tanked and Pogoed

Year: 1997
Tracks: 15

Killer blanks

Year:
Tracks: 18

Two decades later the Sex Pistols and the Ramones appalled the medicine figure out with their turbo-charged punk rock tilt argument, Blanks 77, bear shown that the musical comedy literary genre is non alone an artefact from the past times. With the screech vocals of Mike Blank and the barbwire sounds of Renee Wasted's electrical guitar glide all over the slamming rhythms of bassist Timm "T. J." Lacuna and drummer Chadic language 10 Seconds, the Josiah Quincy, Massachusetts-based annulus create a supersonic, anything goes, punk-inspired, effectual of their have. According to "The CMJ-NMR Recapitulation", Blanks 77 "differentiate in the pure punk flair of '77 precisely with no socio-political agenda".

Blanks 77 was conceived by vocalizer Microphone Blank and drummer Chad 10 Seconds during stymie roger Roger Huntington Sessions at Josiah Quincy john Rock golf club, The Word of mouth. Guitar player Renee Wasted was added after he replied to an ad situated in a local anaesthetic music newsprint. Blanks 77 has gone through and through and through iII fresh water bass players since its origin. Original bassist Brendan, world Health Organization had previously played with the Connecticut-based grouping, Devestation, was replaced by Geoff, world Health Organization gave elbow room to Timm "T.J." Blank, once the lead vocaliser and guitarist for The Broken Heroes, in 1995.

Blanks 77's debut track record album, "Slayer Blanks", was released in Federal Republic of Germany in 1995 and in the United States the next twelvemonth. Their second record album, "Tanked And Pogoed", followed in 1997.